referat.am kursayinner referatner diplomayinner tezer պատվիրել աշխատանքներ description_1 <p>Գրականության ցանկ</p>
<p> </p>
<ol>
<li>A.G Lada, C. Frahm Krick, S.G Kozmin, V. I. Mayorov, T.S Karpova, I. B. Rogozin, and Y.I. Pavlov.Mutator effectsand Mutation Signatures of Editing Deaminases Produced in Bacteia and Yeast. ISSN 0006-2979, Biochemistry (Moscoww) 2011, Vol.76, №1, pp. 131-146.© Pleiades Publishing, Ltd., 2011 Published in Russian in Biokhimiya, 2011, Vol. 76as</li>
<li>A.G Lada, C. Frahm Krick, S.G Kozmin, V. I. Mayorov, T.S Karpova, I. B. Rogozin, and Y.I. Pavlov.Mutator effectsand Mutation Signatures of Editing Deaminases Produced in Bacteia and Yeast. ISSN 0006-2979, Biochemistry (Moscoww) 2011, Vol.76, №1, pp. 131-146.© Pleiades Publishing, Ltd., 2011 Published in Russian in Biokhimiya, 2011, Vol. 76as</li>
<li>Aldrich, M.B. Blackbum. The importance of adenosine deaminase for lymphocyte development and function //Biochem. Biophys.-Ros. Com.-2000.- V.272.- P.311-315</li>
<li>Bhaumik D., Medin J., Gathy K., and Coleman M.S. Mutational analysis of active site residues human adenosine deaminase. J. Biol. Chem. 268, 5464-5470, 1993</li>
<li>Farber G.K. and Petsko G.A. The evolution of alpha/beta barrel enzymes. Trends Biochem. Sci. 15, 228-234, 1990</li>
<li>Franco R., Pacheco R., et al. Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-denitrific cel contacts and allteration of the immune function. Crit. Rev. Immunol., 27, 495-509, 2007</li>
<li>Fernandez J.R., Byrne B., Firestein B.L.; Phylogenetic analysis and molecular evolution of guanine deaminases: from guanine to dendrites //J Mol Evol. 2009 Mar;68(3): 227-35 Epub 2009.Franko</li>
<li>Fernandez J.R., Sweet E. S.; Identification of small molecule compounds with higer binding affinity to guanine deaminase (cipin) than guanine. Bioorganic and Med. Chemistry 18, 6748-6755, 2010.</li>
<li>Gillerman I., et al. Investigations into the origin of the Several Adenosine Deaminase Inhibitors. Jou. Med. Chem., V, 54, p. 107-121, 2011.</li>
<li>Jr. Cytidine deaminase. The 2.3 A<sup>0</sup>crystal structure of an enzyme: transition-state analogcomplex. J. Mol. Biol. 1994.</li>
<li>Ko, T-P.; Lin, J-J.; Hu; C.-Y.; Hsu, Y-H.; Wang. A.H.; Liaw, S.-H. J-Biol. Chem/, 278, 19111, 2003.</li>
<li>Kuzmits, R, Seyfriend, H. Wolf, A. Muller, M. M Enzyme 1980 25, 148</li>
<li>Kusugi T., et al. Binding Gree Energy Calculation of Adenosine Deaminase Inhibitor and the Effect Methyl Substitution Inhibitors. J. Chem. Inf. Model., Vol. 49, No. 3, p. 615-622, 2009.</li>
<li>Liaw, S. H.; Chang Y. J.; Lai, C. T.; Chang H. S.; Chang G.G.; J. Biol. Chem., 279, 35479,2004.</li>
<li>Lishan Yao, Robert I. Cukeier and Honggao Yan /Catalytic mechanisms of guanine deaminase; An ONIOM and Molecular Dynamics Study/ J, Phys. Chem. 2007, 111, 4200-4210.</li>
<li>McCormack, J.J. Marquez, V. E, Liu, P. S, Vistica, D. T Driscoll, J.S. Inhibition of cytidine deaminase by 2-oxopyrimidine riboside and related compounds. Biochem. Pharmacol. 1980 29, 830-832</li>
<li>Murray A.W. The biological significance of purine salvage. Biochem; 40:811-26, 1971.</li>
<li>Niu W., Shu Q Chen Z., Mathews S., Cera E. Frieden C. The Role of Zn<sup>2+</sup> on the structure and stability of Murine Adenosine Deaminase. M. Chem. Soc. J. Phys Chem. B. Vol 114, no. 49. P. 16156-16165, 2010.</li>
<li>Paletzki R.F., Cloning and Characterization of Guanine Deaminase fram Mouse and Rat Brain; USA, Neuroscience Vol. 109 No. 1, pp. 15-26, 2002.</li>
<li>Pospisilova H., Frebort I. Aminohydrolases Acting on adenine, adenosine and their derivatives. Biomed Pap Med. Pal. Olomouc Czech Repub., 151(1):3-10, 2007. Ribarte C, Rochet M, Labedan B, Daignan-Fornier B, Alzari P, Scazzocchio C et al. Sub- families of α/β barrel enzymes: a new adenine deaminase family J. Mol Biol 2003</li>
<li>Saint-Marc C., Daignan-Fornier B.;GUDI (YDL238c) encodes Saccharomyces cerevisiae guanine deaminase, an enzyme axpressed during post-diauxic growth. Yeast.2004 Dec;21(16):1359-63.Sang</li>
<li>Shilova L. N, Gonatar I.P, Zborovskaia I.A., Moskvitina O.V. Antibodies to enzymes of purine metabolism as a factor of gastrointestinal tract lesions in systematic scleroderma. Eskp Klin Gastroenterol.; (1):4-7, 2009..tyler</li>
<li>Shiota G., Fukada J., Ito T., et al. Clinical significance of serum guanase activity in various liver diseases. Jpn J. Med. Vol 28, Nº1,1989.Wang</li>
<li>Wang. L., Hosmane R. S. A unique Ring- expanded acyclic nucleoside analogue htat inhibits both adenosine deaminase and guanine deaminase: Sinthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hidroxyethoxymethil-8-iminoimidazo[4,5-e][1,3]diazepine. Bioorg. & Med. Chem. Letters 11, 2893-2896, 2001.</li>
</ol>
<p style="margin-left:18.0pt">31.Zhang K., et al. Strategy to Fabricate an Electochemical Aptasenor: Application to the</p>
<p style="margin-left:18.0pt">Assey of adenosine deaminase Activity. Am. Chem. Scocity, And. Chem., Vol.82, No.</p>
<p style="margin-left:18.0pt">8, p.3207-3221, 2010.</p>
<p>32.Zelingston D., Zelingston H.;Microdiffusion method for determination nitrogen </p>
<p> liberatedas ammonia. // J. Lab. Clin. Med. V.38.1951.</p>
<p> </p>
<p> </p>
<p> </p>
<p> </p>
<p style="margin-left:36.0pt"> </p>
<p> </p>
<p style="margin-left:36.0pt"> </p>
description_2 <p><strong>Բովանդակություն</strong></p>
<p> </p>
<p>Ներածություն</p>
<p>Գրական ակնարկ</p>
<p>Հետազոտության առարկան և մեթոդները</p>
<p>Փորձնական մաս</p>
<p>Եզրակացություններ</p>
<p>Գրականություն</p>
title_arm Պուրինային և պիրիմիդինային նուկլեոտիդների և նուկլեոզիդների դեզամինացման ուսումնասիրումը C.guilliermondii խմորասնկային բջիջներում title_eng convertot_1 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_2 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_3 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_4 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_5 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_6 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirumy C.guilliermondii xmorasnkayin bjijnerum convertot_7 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii khmorasnkayin bjijnerum convertot_8 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_9 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_10 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirumy C.guilliermondii khmorasnkayin bjijnerum convertot_11 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_13 Purinajin EV pirimidinajin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkajin bjijnerum convertot_14 Purinayin EV pirimidinayin nuklewtidneri EV nuklewzidneri dezaminacman usumnasirum@ C.guilliermondii xmwrasnkayin bjijnerum convertot_15 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bghighnerum convertot_16 Pyrinayin EV pirimidinayin nykleotidneri EV nykleozidneri dezaminacman ysymnasirym@ C.guilliermondii xmorasnkayin bjijnerym convertot_17 Purinayin EV pirimidinayin nukleotidneri EV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum convertot_18 Purinayin YEV pirimidinayin nukleotidneri YEV nukleozidneri dezaminacman usumnasirum@ C.guilliermondii xmorasnkayin bjijnerum